In 2019, San Juan Bautista Regional Hospital was entrusted to HopeXchange and now forms part of the HopeXchange Medical Centers network.

Located in the Jalpatagua region of southeastern Guatemala, near the border of El Salvador, the hospital serves a medically underserved population in Central America. The facility provides a broad range of healthcare services, including an Emergency Department, Medical and Surgical Unit, Obstetrics and Gynecology Department, and Pediatric Unit.

In addition to delivering essential medical care, the medical center focuses on addressing significant health challenges affecting the region, particularly those impacting women and children. The hospital also combats malnutrition through community outreach programs that provide food assistance to vulnerable individuals and families in surrounding villages and communities.